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杰青


1.Jia, X. Tian, Z. Shao, L. Qu, X. Zhao, Q. Tang, J. Tang, G. Liu, W. Cloning, sequencing and genetic characterization of the Chlorothricin gene cluster from Streptomyces antibioticus DSM 40725 as a model for spirotetronate antibiotic biosynthesis. Chem. & Biol. 2006, 13,575-585.

2.Shao, L. Qu, X. Jia, X. Zhao, Q. Tian, Z. Wang, M. Tang, G. Liu, W. Cloning and characterization of a bacterial iterative type I polyketide synthase gene encoding the 6-methylsalicyclic acid synthase. Biochem. Biophys. Res. Commun. 2006, 345, 133-139.

3.Li, L. Deng, W. Song, J. Ding, W. Zhao, Q. Peng, C. Song, W. Tang, G. Liu, W. Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a NRPS system for assembling the unusual tetrapeptidyl skeleton in an iterative manner. J. Bacteriol. 2008, 190, 251-263.

4.Chen, Y. Deng, W. Wu, J. Qian, J. Chu, J. Zhuang, Y. Zhang, S. Liu, W. Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in fermentation of Saccharopolyspora erythraea. Appl. Environ. Microbiol. 2008, 74, 1820-1828.

5.Fang, J. Zhang, Y. Huang, L. Jia, X. Zhang, Q. Zhang, X. Tang, G. Liu, W. Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved stratety fro tetronate biosynthesis in spirotetronate antibiotics. J. Bacteriol. 2008, 190, 6014-6025.

6.Zhao, Q. He, Q. Ding, W. Tang, M. Kang, Q. Yu, Y. Deng, W. Zhang, Q. Fang, J. Tang, G. Liu, W. Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis. Chem. & Biol. 2008, 15, 693-705 (Featured in: Antibiotic biosynthesis: from Genes to Enzymes. Nature China 2008, doi:10.1038/nchina.2008.196).

7.He, Q. Jia, X. Tang, M. Tian, Z. Tang, G. Liu, W. Dissection of two transfer reactions centered on acyl-S-carrier protein intermediates for incorporating 5-chloro-6-methyl-O-methylsalicyclic acid into chlorothricin. ChemBioChem 2009, 10, 813-819.

8.Liao, R. Duan, L. Lei, C. Pan, H. Ding, Y. Zhang, Q. Chen, D. Shen, B. Yu, Y. Liu, W. Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications. Chem. & Biol. 2009, 16, 141-14 (Featured in: Biosynthetic pathway for the production of thiopeptide antibiotics. SciBX 2(10), 2009, Doi: 10.1038/scibx.2009.423).

9. Liu, W. & Yu, Y. Combinatorial Biosynthesis of pharmaceutical natural products. Ed. By Tao, J. & Lin, G. Biocatalysis for the pharmaceutical industry-discovery, development and manufacturing. John Wiley & Sons Pte Ltd, 2009, pp229-245.